University of Wisconsin Small Animal Imaging and Radiotherapy Facility (SAIRF)

The UWCCC SAIRF is dedicated to providing innovative, state-of-the-art, affordable, noninvasive, high-resolution, in-vivo and ex-vivo imaging and radiotherapy support to UWCCC investigators, University of Wisconsin researchers, and industry.

The SAIRF provides access to both full-service and self-service equipment. Full-service equipment is completely operated by the SAIRF staff, from imaging agent injection to scanner operation. Self-service equipment can be operated by trained users. Image analysis training and guidance is offered for all equipment on a fee-for-service basis.

The biomedical community utilizes the SAIRF for mouse lower urinary tract imaging (MRI, µCT, CT/µSPECT).

UW O’Brien Center-Associated Publication Examples:

• McLean D, Rutkowski DR, Liu TT, Hernando D, Ricke WA, Roldán-Alzate A (2019). MRI-based Method for Lower Urinary Tract Dysfunction in Mice. Am J Clin Exp Urol. 2019 Jun 15;7(3):153-158 [eCollection 2019]. PMID 31317054; PMC6627546. https://pubmed.ncbi.nlm.nih.gov/31317054/
• Thomas S, Hao L, DeLaney K, McLean DT, Steinke L, Marker PC, Vezina CM, Li L, Ricke WA (2020). Spatiotemporal Proteomics Reveals the Molecular Consequences of Hormone Treatment in a Mouse Model of Lower Urinary Tract Dysfunction. J Proteome Res. 2020 Apr 3;19(4):1375-1382. PMID 32108482; PMC733919; DOI: 1021/acs.jproteome.9b00451. https://pubmed.ncbi.nlm.nih.gov/32108482/