In a new publication in Brain Communications, Hannah Miles (Pharmaceutical Sciences PhD candidate in the laboratories of Drs. William Ricke & Lingjun Li) and collaborators demonstrate a mechanistic link between aberrant intracellular citrate/acetyl coenzyme A …
Research
UW Scientist Explores Novel Target for Treatment of LUTS
UW SMPH Department of Urology Newsletter Sandra Miller More than half of men over the age of 50 experience lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). While LUTS is a common, …
Researchers at the UW O’Brien Center demonstrate that osteopontin is induced by inflammation and prolongs the inflammatory state
In a new publication in International Journal of Molecular Sciences, researchers at the UW O’Brien Center demonstrate that osteopontin (OPN) is induced by inflammation and prolongs the inflammatory state. Genetic blockade of OPN accelerates recovery …
Researchers at the UW O’Brien Center, in collaboration with UCSF, UMN, Buck Institute, and Loyola University demonstrate that frailty is associated with BPH
In a new publication in JAMA Network Open, UW O’Brien Center researchers and collaborators demonstrate that frailty is independently associated with greater risk of both clinical BPH progression and serious adverse events. See the full …
New research from Dr. Kimberly Keil Stietz implicates perturbations to the immune system in relation to BPC effects on the bladder
New research from Dr. Kimberly Keil Stietz in the UW-Madison Department of Comparative Biosciences implicates perturbations to the immune system in relation to PCB effects on the bladder. See the full text here: https://www.mdpi.com/2305-6304/9/9/214/htm
New research from UW O’Brien Center and UW Department of Urology collaborators demonstrates that metabolic syndrome leads to detrusor hypertrophy and may contribute to impaired bladder function
In a new publication in Urology, researchers at the UW O’Brien Center and UW Department of Urology demonstrate that metabolic syndrome leads to detrusor hypertrophy and may contribute to impaired bladder function, likely related to …
New review from Drs. Douglas Strand and Chad Vezina highlights changing perspectives on the identity of the prostate progenitor
A recent review publication from Dr. Douglas Strand (UTSW) and Dr. Chad Vezina (UW-Madison) describes how recent cellular and anatomical studies are changing our viewpoint on the identity of the prostate progenitor. See the full …
Dr. Kim Keil Stietz and colleagues describe how developmental exposure to PCBs has effects on the bladder
Exciting new research from Dr. Kim Keil Stietz and colleagues at the UW/UTSW/U.Mass-Boston O’Brien Center and Lein Lab at UC Davis describes how developmental exposure to PCBs has effects on the bladder. See full text …
Exciting new work from Drs. vom Saal (University of Missouri), Ricke (UW-Madison), and colleagues!
Exciting new work from Drs. vom Saal (University of Missouri), Ricke (UW-Madison), and colleagues! See the full publication here: https://pubmed.ncbi.nlm.nih.gov/32486162/
New collaborative research from UW-Madison, Florida International University, and the University of Florida demonstrates how timing and concentrations of testosterone are required to work alongside local GLI3 activity to control development of a functional male urogenital tract
New collaborative research from UW-Madison, Florida International University, and the University of Florida demonstrates how timing and concentrations of testosterone are required to work alongside local GLI3 activity to control development of a functional male …