A new collaborative work between the laboratories of Drs. William Ricke and Lingjun Li in the Journal of the American Society for Mass Spectrometry provides insight as to how porous graphitic carbon separations may be appropriately leveraged for glycopeptide identification while raising concerns over quantitative and semiquantitative label-free comparisons as the temperature changes. See the full text here: https://pubs.acs.org/doi/full/10.1021/jasms.2c00249