The Genomics Core service model fills a critical gap in genomics research by offering tailored services that move early ideas through feasibility assessment to project completion. We provide an accessible venue for exploratory, high risk / potentially high pay-off genomics-based studies, especially those that require innovative and/or technically challenging approaches. Do you have an idea that might benefit from single-cell, high-throughput, or re-sequencing approaches? Or secondary validation of gene expression levels using novel technologies like NanoString? Give us a call or shoot us an email! We’re here to help you.
The benign urologic community utilizes the CPCT Genomics Core for gene expression analysis using RNA-sequencing.
UW O’Brien Center-Associated Publication Examples:
- Ruetten H, Wegner KA, Kennedy CL, Turco AE, Zhang HL, Wang P, Sandhu JK, Sandhu SK, Morkrid J, Wang Z, Macoska J, Peterson RE, Bjorling DE, Ricke WA, Marker PC, Vezina CM (2020). Impact of Sex, Androgens, and Prostate Size on C57BL/6J Mouse Urinary Physiology: Urethral Histology. Am J Physiol-Renal Physiol. 2020 Mar 1;318(3):F617-F627. PMID 31904290; PMC7099510; DOI: 1152/ajprenal.00540.2019. https://pubmed.ncbi.nlm.nih.gov/31904290/
- Wang Z, Guzman EC, Nimunkar A, Keil KP, Vezina CM, Ricke WA, Macoska J, Bjorling DE (2019). Void Sorcerer: An Open Source, Open Access Framework for Mouse Uroflowmetry. Am J Clin Exp Urol. 2019 Jun 15;7(3):170-177 [eCollection 2019]. PMID 31317056; PMC6627548; DOI: pending. https://pubmed.ncbi.nlm.nih.gov/31317056/
- Macoska JA, Uchtmann KS, Leverson GE, McVary KT, Ricke WA (2019). Prostate Transition Zone Fibrosis is Associated with Clinical Progression in the Medical Therapy of Prostatic Symptoms (MTOPS) Study. J Urol. 2019 Dec; 202(6):1240-1247 [Epub 2019 Jun 12]. PMID: 31188728; PMC7339116; DOI: 1097/JU.0000000000000385. https://pubmed.ncbi.nlm.nih.gov/31188728/
Biotechnology and Public Data
For more information, please contact:
Dr. Jill Macoska (jill.macoska@umb.edu)